姓名 | 周春华 | 性别 | 男 | |
职称 | 副主任医师 | |||
研究方向 | 1.急、慢性胰腺炎(自身免疫性胰腺炎)基础研究和临床研究 2. 超声内镜临床诊疗及转化研究 3.医工交叉 | |||
电子邮箱 | zhou_chunh@163.com | |||
个人简介 | 周春华,男,中共党员,医学博士,上海交通大学医学院附属瑞金医院消化科副主任、副主任医师,硕士研究生导师,目前主持国家自然科学基金面上项目、青年项目各1项,参与国家自然科学基金面上项目、上海市科委课题、研究者发起的临床研究多项课题。现任中华医学会第12届消化病分会青年委员、设备研发协作组委员、中华医学会消化内镜分会设备研发协作组委员,中国抗癌协会胰腺肿瘤专业委员会委员,上海市第12届消化病分会青年委员会副组长、胰腺病学组副组长、上海市消化内镜分会超声内镜学组委员,海峡两岸医药卫生交流协会消化病学会分会青年委员。临床业务:消化系统常见疾病、多发病诊治,专攻胆道胰腺疾病诊疗,包括超声内镜(EUS-FNA)和ERCP对胆道胰腺疾病的诊治;消化道早癌、黏膜下肿瘤内镜治疗(ESD)。发表SCI收录论文30余篇,中文论文20余篇。 | |||
主要成果 | 近三年发表英文论文: 1. Juanhui Lin, Yuansong Wei, Xiaxian Gu, Miaoru Liu, Mengru Wang, Renxiang Zhou, Duowu Zou, Lichen Yin, Chunhua Zhou, Duanmin Hu. Nanotherapeutics-mediated restoration of pancreatic homeostasis and intestinal barrier for the treatment of severe acute pancreatitis. J Control Release. 2025 Jan 10:377:93-105 共同通讯作者 2. Chunhua Zhou, Jiawei Geng, Hanyi Huang, Lintao Dan, Zhipeng Wu, Xixian Ruan, Yao Zhang, Jie Chen, Jing Sun, Duowu Zou. Adherence to the Mediterranean diet is associated with reduced chronic pancreatitis risk: a longitudinal cohort study. Food Funct. 2024 Nov 11;15(22):11072-11082. 第一作者 3. Xianzheng Qin, Taojing Ran, Benyan Zhang, Chunhua Zhou, Duowu Zou. An unusual case of duodenal neuroendocrine tumor presenting with melena diagnosed by EUS-guided fine-needle biopsy. Endoscopic Ultrasound. 2024 13(3):190-192 共同通讯作者 4. Yaya Bai, Xianzheng Qin, Xiang Ao, Taojing Ran, Chunhua Zhou, Duowu Zou. The role of EUS in the diagnosis of early chronic pancreatitis. Endoscopic Ultrasound.2024. 13(4):232-238 共同通讯作者 5. Kui Wang, Xianzheng Qin, Taojing Ran, Yundi Pan, Yu Hong, Jiawei Wang, Xianda Zhang, XiaoNan Shen, Chenxiao Liu, Xinchen Lu, Yifei Chen, Yaya Bai, Yao Zhang, , Duowu Zou. Causal link between gut microbiota and four types of pancre Chunhua Zhou atitis: a genetic association and bidirectional Mendelian randomization study. Frontiers in microbiology.2023, 23:14:1290202. 共同通讯作者 6. Kui Wang, Suijian Wang, Xianzheng Qin, Yifei Chen, Yuhua Chen, Jiawei Wang, Yao Zhang, Qiang Guo, Chunhua Zhou, Duowu Zou. The causal relationship between gut microbiota and biliary tract cancer: comprehensive bidirectional Mendelian randomization analysis. Front Cell Infect Microbiol. 2024 Mar 15:14:1308742. 共同通讯作者 7. Kui Wang, Suijian Wang, Yuhua Chen, Xinchen Lu, Danshu Wang, Yao Zhang , Wei Pan, Chunhua Zhou, Duowu Zou. Causal relationship between gut microbiota and risk of gastroesophageal reflux disease: a genetic correlation and bidirectional Mendelian randomization study. Front Immunol. 2024 Feb 21:15:1327503. 共同通讯作者 8. Yao Zhang, Jiaxin Wang, Hongxiang Sun, Zhenzhen Xun, Zirui He, Yizhou Zhao, Jingjing Qi, Sishen Sun, Qidi Yang, Yubei Gu, Ling Zhang, Chunhua Zhou, Youqiong Ye, Ningbo Wu, Duowu Zou, Bing Su. TWIST1+FAP+ fibroblasts in the pathogenesis of intestinal fibrosis in Crohn's disease. J Clin Invest. 2024 Jul 18;134(18):e179472. 共同作者 9. Xianzheng Qin, Taojing Ran, Yifei Chen, Yao Zhang, Dong Wang, Chunhua Zhou, Duowu Zou. Artificial Intelligence in Endoscopic Ultrasonography-Guided Fine-Needle Aspiration/Biopsy (EUS-FNA/B) for Solid Pancreatic Lesions: Opportunities and Challenges.Diagnostics 2023, 13(19), 3054; DOI: 10.3390/diagnostics13193054 共同通讯作者 10. Xianzheng Qin, Minmin Zhang, Chunhua Zhou, Taojing Ran, Yundi Pan, Yingjiao Deng, Xingran Xie, Yao Zhang, Tingting Gong, Benyan Zhang, Ling Zhang, Yan Wang, Qingli Li, Dong Wang, Lili Gao, Duowu Zou. A deep learning model using hyperspectral image for EUS-FNA cytology diagnosis in pancreatic ductal adenocarcinoma. Cancer Med. 2023 Aug;12(16):17005-17017. 共同第一作者 11. Xian-Da Zhang, Ling Zhang, Ting-Ting Gong, Zhuo-Ran Wang, Kang-Li Gu, Jun Li, Yuan Chen, Jian-Tao Zhang, Ben-Gong Ye, Jin Ding, Jian-Wei Zhu, Feng Liu, Duan-Min Hu, JianGang Chen, Chun-Hua Zhou, Duo-Wu Zou. A combined radiomic model distinguishing GISTs from leiomyomas and schwannomas in the stomach based on endoscopic ultrasonography images. J Appl Clin Med Phys. 2023 Jul;24(7):e14023. 共同通讯作者 12. Xian-Da Zhang, Yao Zhang, Yi-Zhou Zhao, Chun-Hua Zhou, Duo-Wu Zou. Autoimmune pancreatitis: A bibliometric analysis from 2002 to 2022. Front Immunol. 2023 Feb 22;14:1135096. 共同通讯作者 13. Xian Zheng Qin, Chun Hua Zhou, Ben Yan Zhang, Ling Zhang, Ting Ting Gong, Min Min Zhang, Dong Wang, Duo Wu Zou. Recurrent acute pancreatitis caused by duodenal papillary adenoma: A case report and literature review. J Dig Dis. 2023 Jan;24(1):60-66. 共同作者 14. Jia Jia Xu, Yu Ting Meng, Wen Bin Zou, Jiu Long Zhao, Xue Fang, Yao Zhang, Wei Zhou, Ling Zhang, Kai Xuan Wang, Liang Hao Hu, Zhuan Liao, Chun Hua Zhou, Duo Wu Zou. Cross-sectional evaluation of gut microbial-host co-metabolites in patients with chronic pancreatitis. J Dig Dis. 2023 Feb 16. 共同通讯作者 15. Jinfeng Li, Chunhua Zhou, Jing Zhang, Fei Xu, Yuting Zheng, Shige Wang, Duowu Zou. Photo-induced tumor therapy using MnO2/IrO2-PVP nano-enzyme with TME-responsive behaviors. Colloids Surf B Biointerfaces. 2021 Sep: 205:111852. 共同第一作者 16. Chunhua Zhou, Yao Zhang, Feihu Yan, Yizhou Zhao, Shige Wang, Bingqian Guo, Jia He, Duowu Zou. Vapor deposition synthesis of polypyrrole nanoparticles with a tunable photothermal conversion capacity. Colloids and Surfaces A: Physicochemical and Engineering Aspects,2021, 613,126073 17. Xiaonan Shen#, Chunhua Zhou, Haoran Feng, Jialu Li, Tianxue Xia, Xi Cheng, Ren Zhao, Duowu Zou. ETV1 Positively Correlated With Immune Infiltration and Poor Clinical Prognosis in Colorectal Cancer. Front Immunol. 2022 Jul 4;13:939806. 共同第一作者 近五年主持课题: 1. 肠道间质细胞通过R-spondin3-Wnt通路调控肠Lgr5+干细胞在重症急性胰腺炎肠上皮屏障功能维护中的机制研究,52万,在研,2023-2026 国家自然科学基金(面上项目),主持 2. IL-22激活IL-22R1/STAT3通路调控肠Lgr5+干细胞增殖参与损伤肠上皮修复在重症急性胰腺炎合并肠屏障功能障碍中的机制研究,22万,结题,2019-2021 国家自然科学基金(青年项目),主持 3. IL-22在调控SAP伴肠屏障功能障碍中的机制研究,3万,结题,2019/01-2020/12 江苏省高校自然科学研究项目(面上项目),主持 4. 胆汁酸激活TGR5-EGFR-ERK1/2途径调控胃Lgr5+细胞分化参与反流性胃炎发病的机制研究,25万,结题,2016/01-2021/01,江苏省青年医学重点人才项目,主持 5. 仪实验室样机研发, 地区级,10万,在研,2023/10 - 2026-10,上海交通大学-上海理工大学医工交叉合作项目,主持 6. IBD精准体系的开发与验证, 160万(本中心4.8万),在研,2023/12- 2026/12,国家重点研发计划,课题骨干 近三年专利: 1. 一种活检穿刺标本处理操作平台, 实用新型,2023/06,ZL 2022 2 2563344.6 第一发明人 2. 基于高光谱成像技术的穿刺样本病理分析系统及方法,发明专利,2024/05/03 ZL 2022 1 0863506.X,第六发明人 3. 一种内镜操作护理盘及其使用方法,发明专利,2024/08/13,ZL 2021 1 0638703.7,第三发明人 4. 一种玻片顺序化染色装置, 实用新型,2022/08 ,ZL 2021 2 2990666.4, 第二发明人 5. 一种快速染色装置, 实用新型,2022/08,ZL 2021 2 2988851.X 第二发明人 6. 一种染缸可旋转的自动染色风干装置, 实用新型,2022/08,ZL 2021 2 2901292.4,第二发明人 7. 一种鼻胆管口鼻交换装置, 实用新型,2023/08 ,ZL 2022 2 3084412.7,第三发明人 |