周春华

发布者:沈怡君发布时间:2025-01-03浏览次数:10

姓名

周春华

性别

职称

副主任医师

研究方向

1.急、慢性胰腺炎(自身免疫性胰腺炎)基础研究和临床研究  2. 超声内镜临床诊疗及转化研究 3.医工交叉 

电子邮箱

zhou_chunh@163.com

个人简介

周春华,男,中共党员,医学博士,上海交通大学医学院附属瑞金医院消化科副主任、副主任医师,硕士研究生导师,目前主持国家自然科学基金面上项目、青年项目各1项,参与国家自然科学基金面上项目、上海市科委课题、研究者发起的临床研究多项课题。现任中华医学会第12届消化病分会青年委员、设备研发协作组委员、中华医学会消化内镜分会设备研发协作组委员,中国抗癌协会胰腺肿瘤专业委员会委员,上海市第12届消化病分会青年委员会副组长、胰腺病学组副组长、上海市消化内镜分会超声内镜学组委员,海峡两岸医药卫生交流协会消化病学会分会青年委员。临床业务:消化系统常见疾病、多发病诊治,专攻胆道胰腺疾病诊疗,包括超声内镜(EUS-FNA)和ERCP对胆道胰腺疾病的诊治;消化道早癌、黏膜下肿瘤内镜治疗(ESD)。发表SCI收录论文30余篇,中文论文20余篇。

主要成果

近三年发表英文论文:

1.    Juanhui  Lin, Yuansong Wei, Xiaxian Gu, Miaoru Liu, Mengru Wang, Renxiang Zhou, Duowu  Zou, Lichen Yin, Chunhua Zhou, Duanmin Hu. Nanotherapeutics-mediated  restoration of pancreatic homeostasis and intestinal barrier for the  treatment of severe acute pancreatitis. J Control Release. 2025 Jan  10:377:93-105 共同通讯作者

2.    Chunhua  Zhou, Jiawei Geng, Hanyi Huang, Lintao Dan, Zhipeng Wu, Xixian Ruan, Yao  Zhang, Jie Chen, Jing Sun, Duowu Zou. Adherence to the Mediterranean diet is  associated with reduced chronic pancreatitis risk: a longitudinal cohort  study. Food Funct. 2024 Nov 11;15(22):11072-11082. 第一作者

3.    Xianzheng  Qin, Taojing Ran, Benyan Zhang, Chunhua Zhou, Duowu Zou. An unusual  case of duodenal neuroendocrine tumor presenting with melena diagnosed by  EUS-guided fine-needle biopsy. Endoscopic Ultrasound. 2024    13(3):190-192  共同通讯作者

4.    Yaya  Bai, Xianzheng Qin, Xiang Ao, Taojing Ran, Chunhua Zhou, Duowu Zou.  The role of EUS in the diagnosis of early chronic pancreatitis. Endoscopic  Ultrasound.2024. 13(4):232-238 共同通讯作者

5.    Kui  Wang, Xianzheng Qin, Taojing Ran, Yundi Pan, Yu Hong, Jiawei Wang, Xianda  Zhang, XiaoNan Shen, Chenxiao Liu, Xinchen Lu, Yifei Chen, Yaya Bai, Yao  Zhang, , Duowu Zou. Causal link between gut microbiota and four types of  pancre Chunhua Zhou atitis: a genetic association and bidirectional  Mendelian randomization study. Frontiers in microbiology.2023, 23:14:1290202.  共同通讯作者

6. Kui Wang, Suijian  Wang, Xianzheng Qin, Yifei Chen, Yuhua Chen, Jiawei Wang, Yao Zhang, Qiang  Guo, Chunhua Zhou, Duowu Zou. The causal relationship between gut microbiota  and biliary tract cancer: comprehensive bidirectional Mendelian randomization  analysis. Front Cell Infect Microbiol. 2024 Mar 15:14:1308742. 共同通讯作者

7. Kui Wang, Suijian  Wang, Yuhua Chen, Xinchen Lu, Danshu Wang, Yao Zhang , Wei Pan, Chunhua Zhou,  Duowu Zou. Causal relationship between gut microbiota and risk of  gastroesophageal reflux disease: a genetic correlation and bidirectional  Mendelian randomization study. Front Immunol. 2024 Feb 21:15:1327503. 共同通讯作者

8.    Yao  Zhang, Jiaxin Wang, Hongxiang Sun, Zhenzhen Xun, Zirui He, Yizhou Zhao,  Jingjing Qi, Sishen Sun, Qidi Yang, Yubei Gu, Ling Zhang, Chunhua Zhou,  Youqiong Ye, Ningbo Wu, Duowu Zou, Bing Su. TWIST1+FAP+ fibroblasts in the  pathogenesis of intestinal fibrosis in Crohn's disease. J Clin Invest. 2024  Jul 18;134(18):e179472. 共同作者

9.    Xianzheng  Qin, Taojing Ran, Yifei Chen, Yao Zhang, Dong Wang, Chunhua Zhou,  Duowu Zou. Artificial Intelligence in Endoscopic Ultrasonography-Guided  Fine-Needle Aspiration/Biopsy (EUS-FNA/B) for Solid Pancreatic Lesions:  Opportunities and Challenges.Diagnostics 2023, 13(19), 3054; DOI:  10.3390/diagnostics13193054  共同通讯作者

10.  Xianzheng Qin,  Minmin Zhang, Chunhua Zhou, Taojing Ran, Yundi Pan, Yingjiao Deng,  Xingran Xie, Yao Zhang, Tingting Gong, Benyan Zhang, Ling Zhang, Yan Wang,  Qingli Li, Dong Wang, Lili Gao, Duowu Zou. A deep learning model using  hyperspectral image for EUS-FNA cytology diagnosis in pancreatic ductal  adenocarcinoma. Cancer Med. 2023 Aug;12(16):17005-17017.  共同第一作者

11.  Xian-Da Zhang,  Ling Zhang, Ting-Ting Gong, Zhuo-Ran Wang, Kang-Li Gu, Jun Li, Yuan Chen,  Jian-Tao Zhang, Ben-Gong Ye, Jin Ding, Jian-Wei Zhu, Feng Liu, Duan-Min Hu,  JianGang Chen, Chun-Hua Zhou, Duo-Wu Zou. A combined radiomic model  distinguishing GISTs from leiomyomas and schwannomas in the stomach based on  endoscopic ultrasonography images. J Appl Clin Med Phys. 2023  Jul;24(7):e14023. 共同通讯作者

12.  Xian-Da Zhang,  Yao Zhang, Yi-Zhou Zhao, Chun-Hua Zhou, Duo-Wu Zou. Autoimmune  pancreatitis: A bibliometric analysis from 2002 to 2022. Front Immunol. 2023  Feb 22;14:1135096. 共同通讯作者

13.  Xian Zheng  Qin, Chun Hua Zhou, Ben Yan Zhang, Ling Zhang, Ting Ting Gong, Min Min  Zhang, Dong Wang, Duo Wu Zou. Recurrent acute pancreatitis caused by duodenal  papillary adenoma: A case report and literature review. J Dig Dis. 2023  Jan;24(1):60-66. 共同作者

14.  Jia Jia Xu, Yu  Ting Meng, Wen Bin Zou, Jiu Long Zhao, Xue Fang, Yao Zhang, Wei Zhou, Ling  Zhang, Kai Xuan Wang, Liang Hao Hu, Zhuan Liao, Chun Hua Zhou, Duo Wu  Zou. Cross-sectional evaluation of gut microbial-host co-metabolites in  patients with chronic pancreatitis. J Dig Dis. 2023 Feb 16. 共同通讯作者

15. Jinfeng Li, Chunhua  Zhou, Jing Zhang, Fei Xu, Yuting Zheng, Shige Wang, Duowu    Zou. Photo-induced tumor therapy using MnO2/IrO2-PVP nano-enzyme with  TME-responsive behaviors. Colloids Surf B Biointerfaces. 2021 Sep:  205:111852. 共同第一作者

16. Chunhua Zhou,  Yao Zhang, Feihu Yan, Yizhou Zhao, Shige Wang, Bingqian Guo, Jia He, Duowu  Zou. Vapor deposition synthesis of polypyrrole nanoparticles with a tunable  photothermal conversion capacity. Colloids and Surfaces A: Physicochemical  and Engineering Aspects,2021, 613126073

17.  Xiaonan Shen#,  Chunhua Zhou, Haoran Feng, Jialu Li, Tianxue Xia, Xi Cheng, Ren Zhao,  Duowu Zou. ETV1 Positively Correlated With Immune Infiltration and Poor  Clinical Prognosis in Colorectal Cancer. Front Immunol. 2022 Jul 4;13:939806.  共同第一作者

近五年主持课题:

1  肠道间质细胞通过R-spondin3-Wnt通路调控肠Lgr5+干细胞在重症急性胰腺炎肠上皮屏障功能维护中的机制研究,52万,在研,2023-2026     国家自然科学基金(面上项目),主持

2.    IL-22激活IL-22R1/STAT3通路调控肠Lgr5+干细胞增殖参与损伤肠上皮修复在重症急性胰腺炎合并肠屏障功能障碍中的机制研究,22万,结题,2019-2021      国家自然科学基金(青年项目),主持

3. IL-22在调控SAP伴肠屏障功能障碍中的机制研究,3万,结题,2019/01-2020/12 江苏省高校自然科学研究项目(面上项目),主持

4.    胆汁酸激活TGR5-EGFR-ERK1/2途径调控胃Lgr5+细胞分化参与反流性胃炎发病的机制研究,25万,结题,2016/01-2021/01江苏省青年医学重点人才项目,主持

5. 仪实验室样机研发, 地区级,10万,在研,2023/10 - 2026-10,上海交通大学-上海理工大学医工交叉合作项目,主持

6.    IBD精准体系的开发与验证, 160万(本中心4.8万),在研,2023/12- 2026/12,国家重点研发计划,课题骨干

近三年专利:

1.    一种活检穿刺标本处理操作平台, 实用新型,2023/06ZL 2022 2 2563344.6 第一发明人

2. 基于高光谱成像技术的穿刺样本病理分析系统及方法,发明专利,2024/05/03  ZL  2022 1 0863506.X,第六发明人

3. 一种内镜操作护理盘及其使用方法,发明专利,2024/08/13ZL 2021 1 0638703.7,第三发明人

4. 一种玻片顺序化染色装置, 实用新型,2022/08 ZL 2021 2 2990666.4        第二发明人

5. 一种快速染色装置, 实用新型,2022/08ZL 2021 2 2988851.X  第二发明人

6. 一种染缸可旋转的自动染色风干装置, 实用新型,2022/08ZL 2021 2 2901292.4,第二发明人

7. 一种鼻胆管口鼻交换装置, 实用新型,2023/08 ZL 2022 2 3084412.7,第三发明人

 


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